Custom Liquids High-Resolution NMR Probes 
PFG, Inverse, Electrophoresis, MRI, Quad-Tuned and more

Many in the field of NMR immediately relate Doty Scientific with Solids NMR.  We are proud of our contributions to NMR Solids, however, we would like people to know more about our contributions to liquids NMR as well. Doty Scientific, an established leader in large-sample high-resolution coil technology and solids NMR, is using the latest in laser cutting, compensated laminates, and thermal gradient minimization with alumina coilforms to bring its Super-B1 coils to the field of high-resolution liquids NMR.

Recent results demonstrate the quality and versitility of Doty liquids probes.

¹³C spectrum for a perfused heart in DOTY 25 mm ¹H/X liquids probe at 9.4 T.
The heart was perfused with hyperpolarized 2 mM [1-13C]pyruvate and natural abundance, unpolarized 2 mM octanoate. The metabolic products lactate and alanine are visible after a single 66 degree detection pulse. The octanoate effectively blocks production of the bicarbonate, which would normally be about the size of the lactate. The linewidths were ~12 Hz for ¹³C on the beating heart. Spectrum courtesy of: Dr. Matthew E. Merritt, Assistant Professor, Advanced Imaging Research Center, Southwestern Medical Center at Dallas

NB 1067MHz ¹H/X (with ²H Lock) PFG Diffusion Probe

Spectra Courtesy of Dr Warren Warren (Princeton) and NHMFL, Florida

 

High-Temperature High-Resolution ¹³C spectrum 30 wt % PPS2 in
1-cyclohexyl-2-pyrolidinone at 270°C.

Courtesy of Bruce Wade and A. S. Abhiraman, Georgia Institute of Technology

and by Stephen Wharry and Dirk Sutherlin, Phillips Petroleum.

Following are examples of custom liquids high-resolution          probes designed and built by Doty Scientific :

•  25 mm 1H/X liquids probe at 9.4 T

•  10 mm 1H/ 19F/X/lock, 400 MHz WB, Multi-X, Triple

•  10 mm 1H/X/Y/lock, 500 MHz NB, Multi-X, Multi-Y, Triple

•  10 mm 1H/X/lock, 300 MHz WB, Multi-X, -170°C to 500°C

•  5 mm 1H/X/lock, 600 MHz NB, Inverse, PFG, 220 G/cm continuous

•  5 mm 1H-19F/X/Y, 300 MHz NB, Inverse, Triple, PFG, -170°C to 300°C

•  15 mm 1H/X, 600 MHz NB, Multi-X, Microscopy, 25 G/cm continuous

•  15 mm 1H/19F/X, 600 MHz WB, Electrophoresis, PFG, 140 G/cm continuous

•   40 mm 1H/19F, 400 MHz WB, Microscopy Clear Bore, 14 G/cm continuous

•   18 mm 1H/X/lock, 600 MHz, NB, In-vivo

•   5 mm 1H/X/lock, 1067 MHz (1.07 GHz) NB Multi-X, PFG, 77 G/cm  continuous

•   10 mm 1H/X/lock, 300 MHz High Temp PFG, 500°C

Our discussion of liquids NMR, would not be complete without mention of our OptiMAS^TM probes and the XC MAS probes. These versatile probes were designed specially to provide adequate resolution for the user to do HR MAS on solids, tissues, or liquids.  

Please contact sales with questions or quote requests.