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13C Spectrum of a Perfused Heart
in a DOTY 25 mm 1H/X Liquids Probe at 9.4 T

13C spectrum for a perfused heart in DOTY 25 mm 1H/X liquids probe at 9.4 T. The heart was perfused with hyperpolarized 2 mM [1-13C]pyruvate and natural abundance, unpolarized 2 mM octanoate. The metabolic products lactate and alanine are visible after a single 66 degree detection pulse. The octanoate effectively blocks production of the bicarbonate, which would normally be about the size of the lactate. The linewidths were ~12 Hz for 13C on the beating heart.

Spectrum courtesy of:
Dr. Matthew E. Merritt
Assistant Professor
Advanced Imaging Research Center
Southwestern Medical Center at Dallas