High-Resolution Flatcoil Probes

For Multi-X NMR of Biological Solids

In solid state NMR spectroscopy of stationary, aligned samples, uniaxial orientation provides a mechanism of line-narrowing that retains both the distance and angular information.

Application of proteins and lipids onto glass plates, followed by pressure and shear, results in a very high degree of molecular orientation. This allows for improved structure determinations of macro-molecules using solid-state methods.

DOTY flatcoil probes have :

• Susceptibility-matched coil and housing material for 10 times better resolution and lineshape at all angles, 0.07 ppm FWHM.
• Highest filling factor, B₁ homogeneity, S/N, Q, and B₁ magnitude with oriented membrane samples between glass plates..

Variable Angle Option

Quickly change from parallel to magic-angle to perpendicular

  alignment without removing the probe form the magnet .

The following pictures show a variable angle flat coil probe at orientations (from left to right):

0 degrees, Magic Angle, and 90 degrees.

Examples of B₁ homogeneity from Doty flat-coil probes in the field:

¹H/X 600 MHz wide-bore flat-coil probe, fixed housing,

with 5x10x10 mm sample coil:

Pulse-width array for ¹H (single pulse) on H₂O/D₂O.  Pulses

varied from 1 μs, with 2 μs increments using 100 W ¹H power.

¹H/X 600 MHz wide-bore flatcoil probe, fixed housing,

2.5x7x10 mm sample coil:

Pulse-width array for ¹⁵N (after CP) on ¹⁵N labeled glycine.  

Pulse varied from 1 μs, with 1 μs increments using 1 kW ¹⁵N power.

¹H/ ¹⁹F 500 MHz wide-bore flatcoil probe with

Variable Angle Housing, 2.5x9x10 mm sample coil:

The nearly constant signal intensity with increasing flip angle shows the

            exceptional B₁ homogeneity of the loop gap flat coil for ¹H/ ¹⁹F.

  Please contact sales with questions or quote requests.